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zlzt生物人肺腺癌细胞PC14

发布时间 2022-07-26 收藏 分享
价格 面议
品牌 智立中特生物
区域 全国
来源 智立中特(武汉)生物科技有限公司

详情描述:

细胞名称:人肺腺癌细胞PC14


  产品规格:T25培养瓶x1;1.5ml冻存管x2


  细胞数量:1x10^6;1x10^6


  保存温度:37℃;-198℃


  运输方式:常温保温运输;干冰运输


  安全等级:1


  用途限制:仅供科研2类


  培养体系:DMEM高糖培养基 10%FBS 1%三抗


  培养温度:37℃


  二氧化碳浓度:5%


  简介:人肺腺癌细胞PC14取自45岁男性肺腺癌患者淋巴转移组织,贴壁培养。该细胞源于ECACC


  注释


  Part of:Cancer Cell Line Encyclopedia(CCLE)project.


  Part of:COSMIC cell lines project.


  From:Immuno-Biological Laboratories(IBL);Tokyo;Japan.


  Microsatellite instability:Stable(MSS)(Sanger).


  Omics:Deep exome analysis.


  Omics:Deep quantitative proteome analysis.


  Omics:Deep RNAseq analysis.


  Omics:DNA methylation analysis.


  Omics:SNP array analysis.


  Omics:Transcriptome analysis.


  基因突变


  EGFR p.Glu746_Ala750del(c.2235_2249del15)(PubMed=16105816).


  Homozygous for TP53 p.Arg248Gln(c.743G>A)(PubMed=15901131;Cosmic-CLP).


  HLA信息


  STR信息


  Amelogenin X


  CSF1PO 11


  D5S818 11


  D7S820 10,11(Cosmic-CLP)


  10(ECACC;PubMed=11416159)


  D8S1179 11,15


  D13S317 8


  D16S539 9


  D18S51 15


  D21S11 29,30


  FGA 23,25


  TH01 7


  TPOX 11


  vWA 17


  参考文献


  PubMed=27397505;DOI=10.1016/j.cell.2016.06.017


  Iorio F.,Knijnenburg T.A.,Vis D.J.,Bignell G.R.,Menden M.P.,Schubert M.,Aben N.,Goncalves E.,Barthorpe S.,Lightfoot H.,Cokelaer T.,Greninger P.,van Dyk E.,Chang H.,de Silva H.,Heyn H.,Deng X.,Egan R.K.,Liu Q.,Mironenko T.,Mitropoulos X.,Richardson L.,Wang J.,Zhang T.,Moran S.,Sayols S.,Soleimani M.,Tamborero D.,Lopez-Bigas N.,Ross-Macdonald P.,Esteller M.,Gray N.S.,Haber D.A.,Stratton M.R.,Benes C.H.,Wessels L.F.A.,Saez-Rodriguez J.,McDermott U.,Garnett M.J.


  A landscape of pharmacogenomic interactions in cancer.


  Cell 166:740-754(2016)


  PubMed=30894373;DOI=10.1158/0008-5472.CAN-18-2747


  Dutil J.,Chen Z.,Monteiro A.N.,Teer J.K.,Eschrich S.A.


  An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.


  Cancer Res.79:1263-1273(2019)


  PubMed=31068700;DOI=10.1038/s41586-019-1186-3


  Ghandi M.,Huang F.W.,Jane-Valbuena J.,Kryukov G.V.,Lo C.C.,McDonald E.R.III,Barretina J.,Gelfand E.T.,Bielski C.M.,Li H.,Hu K.,Andreev-Drakhlin A.Y.,Kim J.,Hess J.M.,Haas B.J.,Aguet F.,Weir B.A.,Rothberg M.V.,Paolella B.R.,Lawrence M.S.,Akbani R.,Lu Y.,Tiv H.L.,Gokhale P.C.,de Weck A.,Mansour A.A.,Oh C.,Shih J.,Hadi K.,Rosen Y.,Bistline J.,Venkatesan K.,Reddy A.,Sonkin D.,Liu M.,Lehar J.,Korn J.M.,Porter D.A.,Jones M.D.,Golji J.,Caponigro G.,Taylor J.E.,Dunning C.M.,Creech A.L.,Warren A.C.,McFarland J.M.,Zamanighomi M.,Kauffmann A.,Stransky N.,Imielinski M.,Maruvka Y.E.,Cherniack A.D.,Tsherniak A.,Vazquez F.,Jaffe J.D.,Lane A.A.,Weinstock D.M.,Johannessen C.M.,Morrissey M.P.,Stegmeier F.,Schlegel R.,Hahn W.C.,Getz G.,Mills G.B.,Boehm J.S.,Golub T.R.,Garraway L.A.,Sellers W.R.


  Next-generation characterization of the Cancer Cell Line Encyclopedia.


  Nature 569:503-508(2019)


  PubMed=31978347;DOI=10.1016/j.cell.2019.12.023


  Nusinow D.P.,Szpyt J.,Ghandi M.,Rose C.M.,McDonald E.R.III,Kalocsay M.,Jane-Valbuena J.,Gelfand E.,Schweppe D.K.,Jedrychowski M.,Golji J.,Porter D.A.,Rejtar T.,Wang Y.K.,Kryukov G.V.,Stegmeier F.,Erickson B.K.,Garraway L.A.,Sellers W.R.,Gygi S.P.


  Quantitative proteomics of the Cancer Cell Line Encyclopedia.


  Cell 180:387-402(2020)

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